Cognitive Dysfunction After Carotid Endarterectomy Inducible Nitric Oxide Synthase Promoter Polymorphism Affords Protection Against
نویسندگان
چکیده
Sciacca, Charles W. Emala, Donald O. Quest, Paul C. McCormick, James F. McKinsey, Gene T. Yocum, John G. Gaudet, Susie S. Lee, Yaakov Stern, Lauren A. Teverbaugh, Robert R. Cognitive Dysfunction After Carotid Endarterectomy Inducible Nitric Oxide Synthase Promoter Polymorphism Affords Protection Against Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2009 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Stroke doi: 10.1161/STROKEAHA.108.541177 2009;40:1597-1603; originally published online March 12, 2009; Stroke. http://stroke.ahajournals.org/content/40/5/1597 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Inducible nitric oxide synthase promoter polymorphism affords protection against cognitive dysfunction after carotid endarterectomy.
BACKGROUND AND PURPOSE Cognitive dysfunction occurs in 9% to 23% of patients during the first month after carotid endarterectomy (CEA). A 4-basepair (AAAT) tandem repeat polymorphism (either 3 or 4 repeats) has been described in the promoter region of inducible nitric oxide synthase (iNOS), a gene with complex roles in ischemic injury and preconditioning against ischemic injury. We investigated...
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